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Table 3 Reisolation of the challenge strain from piglets after intranasal challenge with S. suis cps14 strain V3117/2

From: Immunogenicity and protective efficacy of a Streptococcus suis vaccine composed of six conserved immunogens

Immunization

Number of piglets positive for the isolation of the challenge strain in an inner organb or in serosa or in joint fluid

Number of piglets positive for the isolation of the challenge strain in ≥ 3 inner organsb

Number of piglets in which the S. suis challenge straina was isolated from

Tonsil

Lungc

Serosad

Spleen

Liver

Brain, CSFe

Joint fluidf

Endocard

Placebo

3/8

2/8

4/8

2/8

1/8

1/8

1/8

2/8

2/8

1/8

Vaccine

3/8

3/8

6/8

1/8

0/8

2/8

1/8

2/8

3/8

2/8

  1. aThe challenge strain was identified by PCR of all isolates and Sanger sequencing of cpsK locus of five representative isolates from animals showing disseminated infections.
  2. bInner organ refers to lung, spleen, liver, brain, CSF or endocard but not the tonsils.
  3. cOne cranial lobe was investigated.
  4. dPleural, peritoneal or pericardial cavity.
  5. eCerebrospinal fluid.
  6. fPunctures of both tarsal and carpal joints were investigated in each animal. In case of lameness additional joint punctures of the respective limb were screened.
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Veterinary Research

ISSN: 1297-9716