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Figure 4 | Veterinary Research

Figure 4

From: Mutual regulation between chicken telomerase reverse transcriptase and the Wnt/β-catenin signalling pathway inhibits apoptosis and promotes the replication of ALV-J in LMH cells

Figure 4

Wnt/β-catenin and chTERT mutually regulated and promoted the activity/expression of each other. Western blotting (A) and RT-PCR (B) were performed to assess the changes in chTERT expression and the Wnt/β-catenin signalling pathway in LMH-chTERT cells 72 h after siRNA transfection. C Measurement of telomerase activity in LMH-chTERT cells 72 h after transfection of si-chTERT or si-β-catenin. Western blotting (D) and RT-PCR (E) were performed to evaluate the changes in chTERT expression and the β-catenin signalling pathway in LMH-chTERT cells 72 h after treatment with inhibitors (ICG001 and IWP-2) or an activator (LiCl). F Measurement of telomerase activity in LMH-chTERT cells 72 h after treatment with LiCl, ICG001 and IWP-2.

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Veterinary Research

ISSN: 1297-9716