Figure 6

Weighted gene expression co-expression network analysis (WGCNA) of DEGs in equine chorioallantois (CA) during nocardioform placentitis dataset. A Gene module (clusters) identification as determined by WGCNA. B Matrix with the module-trait relationships and corresponding p-values of the modules on the y-axis and selected traits related with treatment on the x-axis. The y-axis is colored according to the correlation, with red representing a strong positive correlation and green representing a strong negative correlation. C Number of genes per module. D, E Module-trait correlation heatmap based on correlation analysis of module eigengenes (MEs) and inflammation score in placenta (n = 12). The turquoise, yellow, and brown modules presented a significant positive correlation with inflammation score (p-values < 0.05). F Over-represented biological process in the turquoise module. G A scatter plot of GS for inflammation score versus the MM in the turquoise module.