Stable trimer formation of spike protein from porcine epidemic diarrhea virus improves the efficiency of secretory production in silkworms and induces neutralizing antibodies in mice

Table 2 The titer of the neutralizing antibody against PEDV in the sera of vaccinated mice

Antigen	Adjuvant	Dose	Number	Titre of neutralizing antibody
Antigen	Adjuvant	Dose	Number	No. 1	No. 2	No. 3	No. 4	No. 5	No. 6	Geometric mean titer
PEDV/S(1–1320) + CMP + Tags	IMS1313	3	6	64	256	128	256	128	1024	203

Sera were collected from the mice vaccinated with PEDV/S(1–1320) + CMP + Tags at 42 days post-vaccination, and a serum neutralization assay was performed using Vero cells to determine the titer of the neutralizing antibody against PEDV.

ISSN: 1297-9716