Figure 2

Crystal structure of hCD163L1 SRCR8 and comparison with pCD163 SRCR5. A The cartoon diagrams of hCD163L1 SRCR8 represented in the 180° rotation. Seven β-strands β1-7, two helices α1-2 and the loop regions are colored as in Figure 1A. The N- and C-termini are labeled. B The ribbon diagrams of hCD163L1 SRCR8 showing the disulfide bonds represented in the 180° rotation as in Figure 1B. C Structural comparison of hCD163L1 SRCR8 with pCD163 SRCR5.The crystal structures of hCD163L1 SRCR8 was aligned with pCD163 SRCR5 in cartoon diagrams. The pCD163 SRCR5 and hCD163L1 SRCR are in green and magenta, respectively. Their N- and C-termini are labeled, and their differences are circled in dashed lines.