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Table 2 Effect of PRRSV infection on intestinal pathology and clinical scores

From: Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection

Parameter Control group PRRSV-infected group P value
Duodenum
 Villus height (μm) 658.1 ± 26.75 459.2 ± 30.79***  < 0.001
 Crypt depth (μm) 342.4 ± 15.06 339.3 ± 14.04 0.8817
 Villus: crypt ratio 1.96 ± 0.12 1.38 ± 0.11** 0.0027
 Lesion score 0.00 1.67 ± 0.75** 0.0041
Jejunum
 Villus height (μm) 567.13 ± 24.80 268.40 ± 19.58***  < 0.001
 Crypt depth (μm) 252.35 ± 22.42 271.27 ± 14.89 0.4913
 Villus: crypt ratio 2.39 ± 0.22 1.01 ± 0.10***  < 0.001
 Lesion score 0.00 2.67 ± 0.47***  < 0.001
Ileum
 Villus height (μm) 499.80 ± 15.86 287.30 ± 14.04***  < 0.001
 Crypt depth (μm) 238.01 ± 15.43 234.40 ± 8.13 0.8364
 Villus: crypt ratio 2.15 ± 0.10 1.24 ± 0.07***  < 0.001
 Lesion score 0.00 2.50 ± 0.50***  < 0.001
  1. Data are expressed as the mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001.