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Table 2 Effect of PRRSV infection on intestinal pathology and clinical scores

From: Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection

Parameter

Control group

PRRSV-infected group

P value

Duodenum

 Villus height (μm)

658.1 ± 26.75

459.2 ± 30.79***

 < 0.001

 Crypt depth (μm)

342.4 ± 15.06

339.3 ± 14.04

0.8817

 Villus: crypt ratio

1.96 ± 0.12

1.38 ± 0.11**

0.0027

 Lesion score

0.00

1.67 ± 0.75**

0.0041

Jejunum

 Villus height (μm)

567.13 ± 24.80

268.40 ± 19.58***

 < 0.001

 Crypt depth (μm)

252.35 ± 22.42

271.27 ± 14.89

0.4913

 Villus: crypt ratio

2.39 ± 0.22

1.01 ± 0.10***

 < 0.001

 Lesion score

0.00

2.67 ± 0.47***

 < 0.001

Ileum

 Villus height (μm)

499.80 ± 15.86

287.30 ± 14.04***

 < 0.001

 Crypt depth (μm)

238.01 ± 15.43

234.40 ± 8.13

0.8364

 Villus: crypt ratio

2.15 ± 0.10

1.24 ± 0.07***

 < 0.001

 Lesion score

0.00

2.50 ± 0.50***

 < 0.001

  1. Data are expressed as the mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001.