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Table 1 Comparisons of MBC and LD50 of the peptides

From: Engineering and characterization of human β-defensin-3 and its analogues and microcin J25 peptides against Mannheimia haemolytica and bovine neutrophils

Peptide

MBC (μg/mL)

LD50 (μg/mL)

HBD3 10AA analogue

6.3

≥ 3.1

HBD3 20AA analogue

50.0

3.1

HBD3 28AA analogue

12.5

3.1

HBD3

50.0

6.3

MccJ25

> 100.0

6.3

  1. MBC (Minimum Bactericidal Concentration) is the concentration of antibiotic at which 99.9% of the CFU in the final inoculum are killed and LD50 is the lethal dose for ≥ 50% of bacteria.
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Veterinary Research

ISSN: 1297-9716