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Table 3 Pairwise comparison of the amino acid sequences of full-length S protein or its individual domains including Domain 0, S1 and S2 domains from GI-a, GI-b, GI-c, and GII genogroup with that of PEDV reference strain virulent CV777 (GenBank ID: AF353511.1)

From: The spike glycoprotein genes of porcine epidemic diarrhea viruses isolated in China

Query: virulent CV777

Full-length

Domain 0

S1 domain

S2 domain

GI-a (n = 9)

99.17 ± 0.29

98.23 ± 0.54

99.48 ± 0.42

99.29 ± 0.24

GI-b (n = 16)

96.77 ± 0.18

96.03 ± 0.07

96.50 ± 0.26

97.30 ± 0.17

GI-c (n = 9)

95.13 ± 0.32

93.07 ± 1.61

95.01 ± 0.15

95.99 ± 0.32

GII (n = 155)

93.79 ± 0.49

85.41 ± 0.86

94.97 ± 0.43

95.97 ± 0.68

  1. The percent amino acid identity (%) was presented as the mean ± standard deviation (SD).