Comparison of linear B cell epitopes affected by amino acid variations in the Domain 0 of S proteins between GI-a strain virulent CV777 and GII strain AJ1102. A The amino acid sequence of predicted linear B cell epitopes are shown with red bold letters. The numbers indicate the amino acid positions relative to the full-length S protein of indicated PEDVs. B 3-dimentional view of epitopes in the Domain 0 of virulent CV777 spike protein. C 3-dimentional view of epitopes in the Domain 0 of AJ1102 spike protein. The tertiary structure was modeled by using I-TASER. The individual epitope is circled and the amino acid variations are labeled with black dot. vCV777, virulent CV777.