Figure 1

Sequence analysis of MnHippo from M. nipponense. A Domain topology of MnHippo-a, MnHippo-b, and MnHippo-c from M. nipponense. B Multiple alignment of amino acid sequences of the three MnHippo isoforms. The black shaded regions represent the identical residues. Other conserved but not consensus amino acids are shaded in grey. C The three-dimensional structure of the S_TKc domain in MnHippo was predicted using the SWISS-MODEL program and PyMOL.