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Table 3 VDJ sequences with identical or high similar CDR3 from four pigs.

From: Chimeric HP-PRRSV2 containing an ORF2-6 consensus sequence induces antibodies with broadly neutralizing activity and confers cross protection against virulent NADC30-like isolate

Pig

No

Name

CDR1

CDR2

CDR3

Pig 3

1

3-R3

SYAVS

YIGSSGR

ARGLAYGAIMDL

3-F18

….

……

…………

2

3-F13

STGII

EVTEDGGL

TLYLTYLDL

3-F23

….

…….

………

3

3-R29

SYEIS

GVDGDRWSG

AGCPLYSGCYIGQLGGVMDL

3-R40

….

………

……………….

Pig 6

1

6-R10

DNAFS

AIASSDYDG

AIG-CYSYGASCYGSYYYAMDL

6-F20

….

………

..QN………DQP--T…

2

6-R27

GSYIN

TISSSGG

ATGLSMVLVAWGAMDL

6-F28

….

……

……………

3

6-F15

DYAFS

AIASSDYDG

ASAVAIAVTFGGRQQYYAMDL

6-F17

….

………

…………………

Pig 12

1a

12-R3b

SYGVV

GIRIS-ISG

AGCAEYYFPYYYSVDL

12-R10

..A.S

..DSGSY.

……W……M.

12-R19

….

……S.

…N..W……I.

12-R28

..A.S

..DSGSY.

……W……M.

12-F3

.V…

A…….

………….M.

12-F5

.V…

A…….

………….M.

Pig 13

1

13-R10

STYIN

FIGTGGA

ARGGCYIGYNCYDMHL

13-F12

….

……

……V………

2

13-R18

DYAFN

GTSKSDYDS

AVGGATIAVAIAVPNAMDL

13-F7

….

………

………………

Pig 14

1

14-R14

SDPIG

RIFSGVS

AAYYEDTMHL

14-F2

….

……

………

14-F16

….

……

………

2

14-R6

SYEIS

GIVSTGS

ARIAIPMVLAIPPYYTMHL

14-R11

….

……

………………

14-R17

….

……

………………

3

14-R10

DTYIS

TISTADA

ARRDSGCANSYVD

14-F19

….

……

…………

4

14-R1

RTYIN

AISIGGV

ARDDFSDYCSASVCGMEL

14-R12

.HD.

……

………………

5

14-F1

SYPIG

DTSTSGG

ATGLMVLSSRTYGAMDL

14-F5

….

……

…………….

6

14-F11

RYEVT

GIDDGTG

AMSYTYGISYDYCGMDR

14-F14

….

……

..G.S…………

  1. aThe shared and abundant sequences (≥ 3 sequences) are highlighted in red. The dot (.) means identical to the first aligned sequence. The short line (-) indicates a deletion. The column No. means the numbers of identical sequences from each pig.
  2. bThe names of VDJ sequences starting with R or F indicate that they are from two different aliquots. The following number denotes the obtained sequence number.