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Table 3 VDJ sequences with identical or high similar CDR3 from four pigs.

From: Chimeric HP-PRRSV2 containing an ORF2-6 consensus sequence induces antibodies with broadly neutralizing activity and confers cross protection against virulent NADC30-like isolate

Pig No Name CDR1 CDR2 CDR3
Pig 3 1 3-R3 SYAVS YIGSSGR ARGLAYGAIMDL
3-F18 …. …… …………
2 3-F13 STGII EVTEDGGL TLYLTYLDL
3-F23 …. ……. ………
3 3-R29 SYEIS GVDGDRWSG AGCPLYSGCYIGQLGGVMDL
3-R40 …. ……… ……………….
Pig 6 1 6-R10 DNAFS AIASSDYDG AIG-CYSYGASCYGSYYYAMDL
6-F20 …. ……… ..QN………DQP--T…
2 6-R27 GSYIN TISSSGG ATGLSMVLVAWGAMDL
6-F28 …. …… ……………
3 6-F15 DYAFS AIASSDYDG ASAVAIAVTFGGRQQYYAMDL
6-F17 …. ……… …………………
Pig 12 1a 12-R3b SYGVV GIRIS-ISG AGCAEYYFPYYYSVDL
12-R10 ..A.S ..DSGSY. ……W……M.
12-R19 …. ……S. …N..W……I.
12-R28 ..A.S ..DSGSY. ……W……M.
12-F3 .V… A……. ………….M.
12-F5 .V… A……. ………….M.
Pig 13 1 13-R10 STYIN FIGTGGA ARGGCYIGYNCYDMHL
13-F12 …. …… ……V………
2 13-R18 DYAFN GTSKSDYDS AVGGATIAVAIAVPNAMDL
13-F7 …. ……… ………………
Pig 14 1 14-R14 SDPIG RIFSGVS AAYYEDTMHL
14-F2 …. …… ………
14-F16 …. …… ………
2 14-R6 SYEIS GIVSTGS ARIAIPMVLAIPPYYTMHL
14-R11 …. …… ………………
14-R17 …. …… ………………
3 14-R10 DTYIS TISTADA ARRDSGCANSYVD
14-F19 …. …… …………
4 14-R1 RTYIN AISIGGV ARDDFSDYCSASVCGMEL
14-R12 .HD. …… ………………
5 14-F1 SYPIG DTSTSGG ATGLMVLSSRTYGAMDL
14-F5 …. …… …………….
6 14-F11 RYEVT GIDDGTG AMSYTYGISYDYCGMDR
14-F14 …. …… ..G.S…………
  1. aThe shared and abundant sequences (≥ 3 sequences) are highlighted in red. The dot (.) means identical to the first aligned sequence. The short line (-) indicates a deletion. The column No. means the numbers of identical sequences from each pig.
  2. bThe names of VDJ sequences starting with R or F indicate that they are from two different aliquots. The following number denotes the obtained sequence number.