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Table 1 Comparison of IgY-scFv and IgY-peptide mimetic detection on clinical samples.

From: Generation and evaluation of IgY-scFv based mimetics against canine parvovirus

Sample IgY-scFv (Mean ± SD) IgY-peptide (Mean ± SD) ICA PCR Sample IgY-scFv (Mean ± SD) IgY-peptide (Mean ± SD) ICA PCR
1 0.52 ± 0.02 0.32 ± 0.00  +   +  16 0.51 ± 0.01 0.48 ± 0.12  +   + 
2 0.52 ± 0.01 0.46 ± 0.03  +   +  17 0.85 ± 0.03 0.99 ± 0.17  +   + 
3 0.59 ± 0.01 0.52 ± 0.02  +   +  18 0.67 ± 0.01 0.59 ± 0.13  +   + 
4 0.14 ± 0.03 0.05 ± 0.00  −   −  19 0.71 ± 0.01 0.54 ± 0.16  +   + 
5 1.51 ± 0.00 0.35 ± 0.04  +   +  20 0.84 ± 0.05 0.31 ± 0.05  +   + 
6 0.11 ± 0.02 0.03 ± 0.01  −   −  21 0.67 ± 0.01 0.32 ± 0.04  +   + 
7 1.99 ± 0.06 1.56 ± 0.35  +   +  22 2.2 ± 0.13 1.43 ± 0.27  +   + 
8 0.56 ± 0.03 0.64 ± 0.02  +   +  23 0.87 ± 0.01 0.59 ± 0.18  +   + 
9 0.82 ± 0.00 0.66 ± 0.03  +   +  24 0.45 ± 0.01 0.32 ± 0.02  +   + 
10 1.1 ± 0.05 0.96 ± 0.03  +   +  25 0.58 ± 0.00 0.93 ± 0.03  +   + 
11 1.47 ± 0.08 0.74 ± 0.04  +   +  26 0.15 ± 0.02 0.04 ± 0.00  −   − 
12 0.14 ± 0.03 0.06 ± 0.01  −   −  27 0.33 ± 0.00 0.51 ± 0.19  +   + 
13 0.83 ± 0.03 0.77 ± 0.03  +   +  28 1.98 ± 0.01 0.96 ± 0.03  +   + 
14 0.86 ± 0.01 0.57 ± 0.05  +   +  NC 0.03 ± 0.02 0.07 ± 0.01   
15 0.84 ± 0.04 0.22 ± 0.04  +   +       
  1. “+” the ICA positive samples, “−” the ICA negative samples; NC, negative control, the sample was replaced by BSA. Statistical principle, P/N > 2.0 (P samples value; N NC value), it can be judged as positive at the level of 99.9%. Results are means of three replicates. The PCR and ICA results were in accordance to [4].