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Figure 1 | Veterinary Research

Figure 1

From: Screening of potential vaccine candidates against pathogenic Brucella spp. using compositive reverse vaccinology

Figure 1

Schematic representation of reverse vaccinology (RV) approaches applied in this study. Pathogenic B. abortus, B. melitensis, and B. suis strains with worldwide geographic distribution were analysed using an RV strategy. Non-host-homology proteins from the core proteome were scored and ranked based on their predicted composite score, and top-ranked proteins were selected as potential vaccine candidates. Three vaccine candidates were evaluated for immunogenicity and protective efficacy in mice.

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Veterinary Research

ISSN: 1297-9716