Table 1 Influence of tonB123 deletion on the susceptibility of A. hydrophila strains to macrolide

WT

32

16

64

128

256

1

128

128

ΔtonB123

2

1

4

16

16

0.125

16

8

ΔtonB123 + ptonB1

16

8

32

64

64

1

64

128

ΔtonB123 + ptonB2

16

8

32

64

64

1

64

128

ΔtonB123 + ptonB3

8

4

16

32

32

0.25

64

64

ΔmacA₁B₁

32

16

64

128

256

1

128

128

ΔtonB123ΔmacA₁B₁

2

1

4

16

16

0.125

16

8

ΔmacA₂B₂

2

1

4

16

16

0.125

16

8

ΔtonB123ΔmacA₂B₂

2

1

4

16

16

0.125

16

8

ΔmacA₂B₂ + pmacA₂B₂

32

16

64

128

256

1

128

128

ΔtonB123ΔmacA₂B₂ + pmacA₂B₂

2

1

4

16

16

0.125

16

8