Figure 5
From: Classical scrapie in small ruminants is caused by at least four different prion strains
Histological analysis of goat TSE isolate transmission in TgBov mice. IHC for PrPSc was performed using the R468 polyclonal antibody. PET blotting was performed using the Sha31 monoclonal antibody. ITNR: Intraneuronal; ITGL: Intra-microglial and intra-astrocytic; PRTC: fine particulate; GLAS: extracellular glia-associated; COAL: Coalescing; LINR: Linear; PLAQ: plaques (vascular and non-vascular); CCtx: Cerebral cortex; Stri: Striatum; Hpp; Hippocampus; Thal: Thalamus; Hpth: Hypothalamus; Midb: Midbrain; CbCtx: Cerebellar cortex; PoMe: Pons/medulla oblongata.