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Table 3 Estimated marginal means of T cell marker surface area (μm2) in cows

From: Prediction of Johne’s disease state based on quantification of T cell markers and their interaction with macrophages in the bovine intestine

 

Status

 

Control

Subclinical

Clinical

CCR9

23.23 ± 1.34

20.98 ± 1.31

140.15 ± 1.31

 Pr(> t)

1.89E−44

2.27E−49

4.12E−89

CD4

585.79 ± 1.23

585.21 ± 1.21

424.80 ± 1.21

 Pr(> t)

6.39E−119

2.05E−129

3.11E−125

CD8α

810.48 ± 1.21

842.23 ± 1.19

514.45 ± 1.19

 Pr(> t)

1.71E−127

5.36E−140

8.33E−132

CXCR3

116.29 ± 14.81

177.98 ± 14.21

1538.85 ± 13.66

 Pr(> t)

4.99E−16

3.42E−27

3.77E−76

FoxP3

1111.78 ± 1.11

711.20 ± 1.10

520.61 ± 1.10

 Pr(> t)

6.61E−177

4.21E−182

1.45E−176

TcR1-N24

1194.59 ± 1.15

1222.86 ± 1.13

506.25 ± 1.13

 Pr(> t)

2.10E−150

3.91E−163

1.87E−148

  1. Estimated marginal means (+ 1 ± SEM) were generated by generalized linear mixed modeling using the following formula: Tcell ~ Status for subclinically (n = 10) and clinically (n = 10) cows infected with MAP, as compared to noninfected control cows (n = 8).
  2. SEM, standard error of the mean; Pr(> t), p-value for t statistic.