Table 4 Summary of the experimental conditions of S. suis co-infection with bacterial pathogens using in vivo models
From: Review of the speculative role of co-infections in Streptococcus suis-associated diseases in pigs
S. suis coinfection pathogen | Age of animals infected with 1st bacterial spp. | Age of animals infected with 2nd bacterial spp. | 1st bacteria route of infection | 2nd bacteria route of infection | 1st bacteria and dose | 2nd bacteria and dose | Conclusions | Refs. |
|---|---|---|---|---|---|---|---|---|
Aerococcus viridans | Five-week-old BABL/c mice | Five-week-old BABL/c mice | IP | IP | 103 – 108 CFU S. suis « novel serotype» (no further details on the strain) | 103 – 108 CFU A. viridians | ↑ Mortality | [137] |
Bordetella bronchiseptica | Five-day old germ-free piglets | Seven-day-old germ-free piglets | IN | IN | 0.5 × 107 CFU B. bronchiseptica | 0.7 × 106 CFU; serotype 2, ST1, different phenotypes | ↑ Clinical signs | [141] |