Figure 9

Visualization of the identified differentially-expressed miRNAs and their target genes as an interaction network based on the common target genes (CoPS vs. H). Blue squares represent differentially-expressed miRNAs, orange circles denote target genes, and green circles represent target genes common to 2 or more miRNAs. miRNet web application [67]. The abbreviations and full names of the target genes common to 2 or more miRNAs: POLR3H—RNA Polymerase III Subunit H, SARM1—Sterile Alpha And TIR Motif Containing 1, KCTD17—Potassium Channel Tetramerization Domain Containing 17, MAPK14—Mitogen-Activated Protein Kinase 14, CERS3—Ceramide Synthase 3, SHISA5—Shisa Family Member 5, SLC25A25—Solute Carrier Family 25 Member 25, PACSIN1—Protein Kinase C And Casein Kinase Substrate In Neurons 1, ADGRD1—Adhesion G Protein-Coupled Receptor D1, MOGAT2—Monoacylglycerol O-Acyltransferase 2, TULP3—TUB Like Protein 3, DES—Desmin, ASB5—Ankyrin Repeat And SOCS Box Containing 5, ZFAND3—Zinc Finger AN1-Type Containing 3, GTPBP2—GTP Binding Protein 2, SP7—Sp7 Transcription Factor, CLIC3—Chloride Intracellular Channel 3, KRT80—Keratin 80, NR4A3—Nuclear Receptor Subfamily 4 Group A Member 3, PHYHIP—Phytanoyl-CoA 2-Hydroxylase Interacting Protein, LOC100298356—Uncharacterized protein, PERM1—PPARGC1 And ESRR Induced Regulator, Muscle 1, PGAP3—Post-GPI Attachment To Proteins 3, SHC1—SHC Adaptor Protein 1, IL10RB—Interleukin 10 Receptor Subunit Beta, CLIP2—CAP-Gly Domain Containing Linker Protein 2, CALHM2—Calcium Homeostasis Modulator Family Member 2, SLC39A13—Solute Carrier Family 39 Member 13, SPI1—Spi-1 Proto-Oncogene, NACC1—Nucleus Accumbens Associated 1, SSH2—Slingshot Protein Phosphatase 2, DLC1—DLC1 Rho GTPase Activating Protein, CTSC—Cathepsin C, TNFAIP8—TNF Alpha Induced Protein 8, FGF7—Fibroblast Growth Factor 7, BTG2—BTG Anti-Proliferation Factor 2, TNF—Tumor Necrosis Factor, IL6—Interleukin 6.