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Figure 3 | Veterinary Research

Figure 3

From: A novel fiber-2-edited live attenuated vaccine candidate against the highly pathogenic serotype 4 fowl adenovirus

Figure 3

Pathogenicity of the recombinant virus FA4-EGFP in vivo. SPF chickens were randomly divided into three groups and then infected with FA4-EGFP, WT FAdV-4, and 1% culture medium, respectively. The clinical symptoms and mortality of the infected chickens were monitored daily, and the liver, spleen, kidney, and cloacal swabs were collected for viral titration at the indicated time points. A Percent of survival for these infected chickens. B Representative histological changes in liver tissues from chickens infected with FA4-EGFP (a) and wild-type FAdV-4 (b). Viral shedding in cloacal swabs from chickens of different groups. C Viral loads in the liver (D), spleen (E), and kidney (F) tissues from these infected chickens of different groups.

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Veterinary Research

ISSN: 1297-9716