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Figure  1 | Veterinary Research

Figure  1

From: Streptococcus suis serotype 2 enolase interaction with host brain microvascular endothelial cells and RPSA-induced apoptosis lead to loss of BBB integrity

Figure  1

Eno destroys BBB model integrity. A co-culture BBB model was established successfully; B Eno disrupts BBB integrity based on TEER; C Rabbit anti-Eno IgG inhibits SS2 penetration into the BBB; D Effect of anti-Eno on the TEER of the SS2-treated BBB model; E, F, BL21-Eno has stronger adhesion to and invasion into PBMECs and has a stronger ability to cross the BBB than does BL21-23a (n = 3); (606 = SS2 strain CVCC606, anti-Eno = rabbit anti-Eno IgG, anti-Negative = isotype IgG control, i.e., same as anti-Eno, *p < 0.05, **p < 0.01, NSp > 0.05).

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