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Table 6 Details of immunological diagnosis in African lion.

From: Diagnosis of tuberculosis in wildlife: a systematic review

Assay test N/E nSe + nSp Antigens Se (%) Sp (%) References
SIT N 52 + 32
44
bPPD 86.5
NE
81.2
100a
[62]
SCITT N 52 + 32
44
bPPD, aPPD 80.8
NE
81.2
100a
[62]
N 8 bPPD, aPPD 63 NE [115]
Elephant
TB
Stat-Pak
N 11 ESAT-6, CFP-10, MPB83 64 NE [115]
DPP Vet TB N 10 ESAT-6, CFP-10, MPB83 70 NE [115]
  1. N/E: natural or experimental infection; nSe: number of TB positive animals used for evaluation of Se; nSp: number of TB negative animals used for evaluation of Sp; Se: sensitivity; Sp: specificity; SIT: single intradermal cervical test; SCITT: single comparative intradermal tuberculin skin test: NE: not estimated; Elephant TB Stat-Pak and DPP Vet TB are lateral flow rapid tests (Chembio Diagnostic Systems, Inc., USA).
  2. a Sp of the test when 44 samples from uninfected population are considered and only 11 of which are tested negative by culture.
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