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Table 6 Details of immunological diagnosis in African lion.

From: Diagnosis of tuberculosis in wildlife: a systematic review

Assay test

N/E

nSe + nSp

Antigens

Se (%)

Sp (%)

References

SIT

N

52 + 32

44

bPPD

86.5

NE

81.2

100a

[62]

SCITT

N

52 + 32

44

bPPD, aPPD

80.8

NE

81.2

100a

[62]

N

8

bPPD, aPPD

63

NE

[115]

Elephant

TB

Stat-Pak

N

11

ESAT-6, CFP-10, MPB83

64

NE

[115]

DPP Vet TB

N

10

ESAT-6, CFP-10, MPB83

70

NE

[115]

  1. N/E: natural or experimental infection; nSe: number of TB positive animals used for evaluation of Se; nSp: number of TB negative animals used for evaluation of Sp; Se: sensitivity; Sp: specificity; SIT: single intradermal cervical test; SCITT: single comparative intradermal tuberculin skin test: NE: not estimated; Elephant TB Stat-Pak and DPP Vet TB are lateral flow rapid tests (Chembio Diagnostic Systems, Inc., USA).
  2. a Sp of the test when 44 samples from uninfected population are considered and only 11 of which are tested negative by culture.