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Table 2 Details of immunological diagnosis in wild suids.

From: Diagnosis of tuberculosis in wildlife: a systematic review

Assay test

Species

N/E

nSe + nSp

Antigen

Se (%)

Sp (%)

References

Skin test (SCITT)

Eurasian wild boar

E

4 + 31

bPPD, aPPD

77-100a

48.4–77.4a

[22]

 

Common warthog

N

16 + 18

bPPD, aPPD

81

100

[8]

Skin test (SIT)

Common warthog

N

16 + 18

bPPD, aPPD

69

100

 

ELISA- protein G

Eurasian wild boar

N

96 + 104

bPPD

79.2

100

[133]

ELISA- IgG

Eurasian wild boar, domestic pig

N

277 + 366

bPPD

P22

77.3

84.1

97.3

98.4

[25]

Eurasian wild boar

N

E

30 + 25

51 + 9

P22

P22

96.7

84.3

100

100

[125]

ELISA- protein A&G

Eurasian wild boar

N

22 + 43

MPB83

86

100

[149]

Common warthog

N

16 + 19

bPPD

88

89

[97]

Common warthog

N

25

bPPD

92

NE

[150]

ELISA TB-VK

Eurasian wild boar

N

73 + 112

bPPD

72.6

96.4

[137]

Common warthog

N

16 + 19

bPPD

88

79

[97]

Common warthog

N

25

bPPD

86

NE

[150]

ELISA-INgezim TB porcine

Eurasian wild boar

N

E

30 + 25

51 + 9

MPB70, MPB83

100

92.1

100

100

[126]

INgezim

Tuberculosis DR

Eurasian wild boar

N

E

30 + 25

51 + 9

MPB83

93.3

86.2

100

100

[125]

RT

Eurasian wild boar

N

64 + 113

ESAT-6, CFP-10, MPB83

76.6

97.3

[109]

DPP VetTB

Warthog Eurasian wild boar

N

23 + 35

56 + 30

ESAT-6, CFP-10, MPB83

82.6

80.4

91.4

96.7

[110]

Eurasian wild boar

N

96 + 104

ESAT-6, CFP-10, MPB83

89.6

90.4

[133]

Common warthog

N

16 + 19

ESAT-6, CFP-10, MPB83

75

89

[97]

INgezim TB-CROM

Eurasian wild boar

N

E

30 + 25

51 + 9

MPB83

93.3

90.2

96

100

[125]

  1. N/E: natural or experimental infection; Se: sensitivity; Sp: specificity; nSe: number of TB positive animals used for evaluation of Se; nSp: number of TB negative animals used for evaluation of Sp; a range of values due to the difference in reading criteria; SIT: single intradermal tuberculin test; SCITT: single comparative intradermal tuberculin skin test; IGRA: interferon gamma assay; ELISA: enzyme linked immunosorbent assay; ELISA TB-VK: Commercial ELISA kit (Vacunek, Spain); ELISA- INgezim TB porcine and INgezim Tuberculosis DR: Commercial ELISA kit (INGENASA, Spain); RT: lateral flow rapid test (name not mentioned-Chembio Diagnostic Systems, Inc., USA); DPP VetTB: rapid lateral flow kit (Chembio Diagnostic Systems, Inc., USA), INgezim TB-CROM: rapid lateral flow kit (INGENASA S.L., Spain).