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Table 2 Details of immunological diagnosis in wild suids.

From: Diagnosis of tuberculosis in wildlife: a systematic review

Assay test Species N/E nSe + nSp Antigen Se (%) Sp (%) References
Skin test (SCITT) Eurasian wild boar E 4 + 31 bPPD, aPPD 77-100a 48.4–77.4a [22]
  Common warthog N 16 + 18 bPPD, aPPD 81 100 [8]
Skin test (SIT) Common warthog N 16 + 18 bPPD, aPPD 69 100  
ELISA- protein G Eurasian wild boar N 96 + 104 bPPD 79.2 100 [133]
ELISA- IgG Eurasian wild boar, domestic pig N 277 + 366 bPPD
P22
77.3
84.1
97.3
98.4
[25]
Eurasian wild boar N
E
30 + 25
51 + 9
P22
P22
96.7
84.3
100
100
[125]
ELISA- protein A&G Eurasian wild boar N 22 + 43 MPB83 86 100 [149]
Common warthog N 16 + 19 bPPD 88 89 [97]
Common warthog N 25 bPPD 92 NE [150]
ELISA TB-VK Eurasian wild boar N 73 + 112 bPPD 72.6 96.4 [137]
Common warthog N 16 + 19 bPPD 88 79 [97]
Common warthog N 25 bPPD 86 NE [150]
ELISA-INgezim TB porcine Eurasian wild boar N
E
30 + 25
51 + 9
MPB70, MPB83 100
92.1
100
100
[126]
INgezim
Tuberculosis DR
Eurasian wild boar N
E
30 + 25
51 + 9
MPB83 93.3
86.2
100
100
[125]
RT Eurasian wild boar N 64 + 113 ESAT-6, CFP-10, MPB83 76.6 97.3 [109]
DPP VetTB Warthog Eurasian wild boar N 23 + 35
56 + 30
ESAT-6, CFP-10, MPB83 82.6
80.4
91.4
96.7
[110]
Eurasian wild boar N 96 + 104 ESAT-6, CFP-10, MPB83 89.6 90.4 [133]
Common warthog N 16 + 19 ESAT-6, CFP-10, MPB83 75 89 [97]
INgezim TB-CROM Eurasian wild boar N
E
30 + 25
51 + 9
MPB83 93.3
90.2
96
100
[125]
  1. N/E: natural or experimental infection; Se: sensitivity; Sp: specificity; nSe: number of TB positive animals used for evaluation of Se; nSp: number of TB negative animals used for evaluation of Sp; a range of values due to the difference in reading criteria; SIT: single intradermal tuberculin test; SCITT: single comparative intradermal tuberculin skin test; IGRA: interferon gamma assay; ELISA: enzyme linked immunosorbent assay; ELISA TB-VK: Commercial ELISA kit (Vacunek, Spain); ELISA- INgezim TB porcine and INgezim Tuberculosis DR: Commercial ELISA kit (INGENASA, Spain); RT: lateral flow rapid test (name not mentioned-Chembio Diagnostic Systems, Inc., USA); DPP VetTB: rapid lateral flow kit (Chembio Diagnostic Systems, Inc., USA), INgezim TB-CROM: rapid lateral flow kit (INGENASA S.L., Spain).
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