Figure 4From: Specific EtMIC3-binding peptides inhibit Eimeria tenella sporozoites entry into host cellsEffect of three target peptides in inhibiting sporozoites invasion of cells in vitro. The three target peptides, especially peptide A showed obvious effects in inhibiting sporozoites invasion of MDBK cells. The inhibition ratio showed in dose-dependent manners with concentraion of three peptides ranging from 25 to 125 μg/mL, showing inhibition ratio of 71.8% for peptide A, 54.6% for D and 20.8% for W at concentration of 125 μg/mL. 300 μg/mL of prepared polyclonal antisera against EtMIC3-b1c protein was used as positive control, showing inhibition ratio of 75.2%. The values represent mean ± SD (n = 5). ∗ P < 0.05, ∗  ∗ P < 0.01.Back to article page