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Figure 6 | Veterinary Research

Figure 6

From: Regulatory effects of chicken TRIM25 on the replication of ALV-A and the MDA5-mediated type I interferon response

Figure 6

Effects of overexpression (A) and knockdown (B) of chicken TRIM25 on mRNA expression ofMDA5, MAVS and IFN-β induced by poly(I:C) in DF1 cells. Different letters on the bars indicate statistically significant differences (P < 0.05) and the same letter indicates no significant difference (P > 0.05) between the groups. The TRIM25-GFP plasmid, TRIM25-siRNA, GFP plasmid and NC-siRNA were transfected into DF1 cells, respectively; and 2 μg/mL poly(I:C) were transfected at 4 h post-first-transfection, then the cell samples were collected for detection at 120 h post-second-transfection.

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Veterinary Research

ISSN: 1297-9716