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Table 5 Ex vivo AUC24h/MIC values of Streptococcus equi subsp. equi strain (mean ± SEM, n = 6) after IM administrations of cefquinome (1 mg/kg)

From: Pharmacokinetic and pharmacodynamic integration for optimal dosage of cefquinome against Streptococcus equi subsp. equi in foals

Serum samples (h) AUC24h/MIC (h) E (log cfu/mL)
0 0 4.39
.5 765 ± 112.41 −5
1 1277.5 ± 145.12 −6.3
2 1675 ± 182.23 −6
4 777.5 ± 170.35 −6.3
8 500 ± 78.04 −6
12 177.5 ± 16.43 −4.69
24 75 ± 17.54 3.48