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Table 5 Ex vivo AUC24h/MIC values of Streptococcus equi subsp. equi strain (mean ± SEM, n = 6) after IM administrations of cefquinome (1 mg/kg)

From: Pharmacokinetic and pharmacodynamic integration for optimal dosage of cefquinome against Streptococcus equi subsp. equi in foals

Serum samples (h)

AUC24h/MIC (h)

E (log cfu/mL)

0

0

4.39

.5

765 ± 112.41

−5

1

1277.5 ± 145.12

−6.3

2

1675 ± 182.23

−6

4

777.5 ± 170.35

−6.3

8

500 ± 78.04

−6

12

177.5 ± 16.43

−4.69

24

75 ± 17.54

3.48

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Veterinary Research

ISSN: 1297-9716