Figure 10

Specific antibody responses in mice vaccinated with rTsP. A Specific total IgG in mice immunized with rTsP, the adjuvant ISA 201 or PBS at different time points after vaccination. Specific IgG1 (B) and IgG2a (C) subclass responses against rTsP at different times after vaccination. The OD values from each group are shown as the mean ± SD of antibody levels (n = 20). The vaccination times are indicated by arrows (↑). *P < 0.0001 compared to the ISA 201 adjuvant or PBS group.