Veterinary Research

Table 3 **Presence (+) or absence (-) of individual ABZ metabolites (M1–M13) in homogenates and medium ofH. contortus adultspreincubated without (0) or with ABZ in sub-lethal doses (0.01, 0.1 and 1 µM)**

From: Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults

Metabolite designation	Homogenate of H. contortus								Medium
	Female				Male				Female				Male
	0	0.01	0.1	1	0	0.01	0.1	1	0	0.01	0.1	1	0	0.01	0.1	1
M1_ABZ	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
M2_ABZ	−	+	+	+	−	−	−	+	−	−	−	−	−	−	−	−
M3_ABZ	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
M4_ABZ	−	−	+	+	−	−	−	−	+	+	+	+	−	−	+	+
M6_ABZ	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
M7_ABZ	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
M8_ABZ	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
M9_ABZ	+	+	+	+	+	+	+	+	−	+	+	+	−	+	+	+
M10_ABZ	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
M11_ABZ	+	+	+	+	−	−	+	+	−	+	+	+	−	−	+	+
M12_ABZ	−	+	+	+	−	−	−	−	−	+	+	+	−	−	−	−
M13_ABZ	−	−	+	+	−	−	−	−	−	−	−	+	−	−	−	−
ABZ	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+

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ISSN: 1297-9716

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