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Figure 7 | Veterinary Research

Figure 7

From: Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults

Figure 7Figure 7

The comparison of the amounts of individual metabolites presented in homogenate and cultivation medium of male (M) and female (F) ofH. contortusadults after 12 h incubation in 10 µM ABZ concentration with prior 18 h pre-incubation with ABZ at 0.01, 0.1 and 1.0 µM concentrations or without. Individual metabolites: M1 and M2 (N-glycoside of ABZSO; A, B, M3 (ABZSO; C), M4 (N-glycoside of hydrolyzed ABZ; D), M6 (ABZ-sulfone; E), M7, M8 and M9 (N-glycoside of ABZ; F–H), M10–M13 (acetylglycoside of ABZ; I–L). The data represent the mean ± S.D. (n = 3). An asterisk (*) indicates a significant difference (P < 0.05) compared to pre-incubation without ABZ concentration. n.d. = not detected.

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Veterinary Research

ISSN: 1297-9716