Figure 4

Mouse serum anti-fimbriae IgG antibody titers (log10) from SC immunized with FaeG–FedF–FanC–FasA–Fim41a MEFA protein. A Titration of anti-FaeG, FedF, FanC, FasA, and Fim41a IgG antibodies in serum samples of the FaeG–FedF–FanC–FasA–Fim41a MEFA protein immunized mice (filled circle) and control mice (open circle). Each circle represents the IgG titer from a single mouse. Bars indicate the mean titers of the group specific to each fimbria. Antibody titers are presented as log₁₀. B Comparison of the specific anti-fimbriae antibody titers between the co-administration group and FaeG–FedF–FanC–FasA–Fim41a MEFA group. *Statistically significant difference when compared to the co-administration group (P < 0.05), **Statistically significant difference when compared to the co-administration group (P < 0.01).