Figure 2

Clinical and pathology assessment of the pigs from different treatment groups after challenge. A Average daily weight gain (ADG) calculated from challenge to necropsy by treatment group. The ADG for pigs in multiple groups are summarized as the boxplots in grams and each data point represents an individual pig. The dark blue, green and dark red bars and data points represent the pigs from the whole inactivate vaccine comparisons, negative control and live attenuate vaccine comparison groups respectively. B Individual pig body temperature (°C) values by group from day prior to inoculation to necropsy. The daily body temperature (°C) for pigs in different treatment group are summarized as mean (± SEM) by bar plots and each data point represents an individual pig. The dark blue, green and dark red bars and data points represent the pigs from the whole inactivated vaccine comparisons, negative control and live attenuated vaccine comparison groups respectively. The 40.0 centigrade was set up as the threshold for fever and represented as the horizontal line. C The gross lung lesions for pigs at necropsy by treatment groups. The gross lung lesions for pigs are shown as percentage and presented by boxplots. Each data point indicates an individual pig. The colors for boxplots and data points are same as in A.