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Figure  2 | Veterinary Research

Figure  2

From: Crosstalk between Neospora caninum and the bovine host at the maternal-foetal interface determines the outcome of infection

Figure  2

Comparison of the immunohistochemical labelling of MMP, TIMPs and ECM components. The distribution of MMP-2 (A), MMP-14 (B) and TIMP-2 (C) is shown in placentomes from uninfected animals (G-control) and Nc-Spain7- and Nc-Spain1H-infected animals at 10 and 20 dpi. Increased immunoreactivity of MMP-14 was detected in Nc-Spain1H-infected placentomes at 10 dpi. At 20 dpi, a loss of MMP-2, MMP-14 and TIMP-2 staining was observed in the lytic areas of the Nc-Spain7-infected placentomes. Brownish staining indicates a positive reaction. For the magnification, see the bar in each individual image. Three randomly selected medial placentomes from each animal were analysed.

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