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Figure 6 | Veterinary Research

Figure 6

From: Dihydromyricetin attenuates Escherichia coli lipopolysaccharide-induced ileum injury in chickens by inhibiting NLRP3 inflammasome and TLR4/NF-κB signalling pathway

Figure 6

0.025%, 0.05% and 0.1% DHM inhibited inflammasome formation and pyroptosis activation in LPS-induced ileum injury. Changes of NLRP3 (A), caspase-1 (B) IL-1β (C) and IL-18 (D) mRNA expression levels and IL-1β (E) and IL-18 (F) contents in ileum after 60 mg/kg LPS exposure for 12 h followed by 14 days of 0.025%, 0.05% and 0.1% DHM treatment. Values are expressed as the mean ± SD for each group (n = 5). *p < 0.05 and **p < 0.01 represented all groups compared with the control group. #p < 0.05 and ##p < 0.01 represented all groups compared with the LPS group.

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