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Table 5 Top 25 up- and downregulated DEGs in the head kidney at 24 and 72 hpi.

From: RNA-Seq analysis of European sea bass (Dicentrarchus labrax L.) infected with nodavirus reveals powerful modulation of the stress response

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Blast2GO UniProt/SwissProt description FC Blast2GO UniProt/SwissProt description FC
24 hpi
 Cytochrome P450 11B, mitochondrial (CP11B) 7007.72    Transcription cofactor vestigial-like protein 4 (VGLL4) −88.03
 Steroidogenic acute regulatory protein, mitochondrial (STAR) 1423.20    Keratin, type I cytoskeletal 13 (K1C13) −71.73
 Cytochrome P450 11B, mitochondrial (CP11B) 453.32    NLR family CARD domain-containing protein 3 (NLRC3) −64.71
 Steroid 21-hydroxylase (CP21A) 349.77    Keratin, type II cytoskeletal 8 (K2C8) −60.16
 Steroid 21-hydroxylase (CP21A) 326.02    Translocase of chloroplast 34 homolog, chloroplastic (TOC34) −15.80
 Steroid 17-alpha-hydroxylase/17,20 lyase (CP17A) 307.93    Carbonic anhydrase 1 (CAH1) −5.18
 Steroid 17-alpha-hydroxylase/17,20 lyase (CP17A) 95.58   
 3 beta-hydroxysteroid dehydrogenase/Delta 5– > 4-isomerase type 1 (3BHSD) 61.79   
 Nuclear receptor subfamily 5 group A member 2 (NR5A2) 43.00   
Chemokine-like receptor 1 (CML1) 17.97   
 Cholesterol side-chain cleavage enzyme, mitochondrial (CP11A) 4.37   
72 hpi
 Acidic mammalian chitinase (CHIA) 32.07    Contactin-associated protein-like 5 (CNTP5) −39.47
 Transposon Ty3-I Gag-Pol polyprotein (YI31B) 10.35    Elongation factor 1-gamma (EF1G) −32.60
 Myosin-binding protein C, fast-type (MYPC2) 6.51    Phosphoserine aminotransferase (PSAT) −6.24
 Fructose-bisphosphate aldolase A (ALDOA) 5.12    Lanosterol 14-alpha demethylase (CP51A) −6.08
 Neuronal acetylcholine receptor subunit beta-4 (ACHB4) 2.84    D-3-phosphoglycerate dehydrogenase (3-PGDH) −5.03
 Glyceraldehyde-3-phosphate dehydrogenase (G3P) 2.75    Calreticulin (CALR) −4.42
 Rieske domain-containing protein (RFESD) 2.08    Protein FAM111A (F111A) −4.16
      Calreticulin (CALR) −3.74
      Mitochondrial glutamate carrier 1 (GHC1) −3.43
      Arachidonate 12-lipoxygenase, 12R-type (LX12B) −3.20
      Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3) −3.06
      Fibronectin (FINC) −3.05
      Argininosuccinate synthase (ASSY) −3.04
      Quinone oxidoreductase PIG3 (QORX) −2.88
      Calreticulin (CALR) −2.76
      Stromal cell-derived factor 2-like protein 1 (SDF2L) −2.75
      Endoplasmic reticulum chaperone BiP (BIP) −2.71
      Inositol-3-phosphate synthase 1-A (INO1A) −2.69
      Protein disulfide-isomerase A6 (PDIA6) −2.63
      Spermidine synthase (SPEE) −2.62
      Nuclear mitotic apparatus protein 1 (NUMA1) −2.49
      Protein disulfide-isomerase A4 (PDIA4) −2.47
      Rac GTPase-activating protein 1 (RGAP1) −2.45
      L-lactate dehydrogenase A chain (LDHA) −2.40
      Histone chaperone asf1b-B (AS1BB) −2.36