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Table 5 Top 25 up- and downregulated DEGs in the head kidney at 24 and 72 hpi.

From: RNA-Seq analysis of European sea bass (Dicentrarchus labrax L.) infected with nodavirus reveals powerful modulation of the stress response

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Blast2GO UniProt/SwissProt descriptionFCBlast2GO UniProt/SwissProt descriptionFC
24 hpi
 Cytochrome P450 11B, mitochondrial (CP11B)7007.72   Transcription cofactor vestigial-like protein 4 (VGLL4)−88.03
 Steroidogenic acute regulatory protein, mitochondrial (STAR)1423.20   Keratin, type I cytoskeletal 13 (K1C13)−71.73
 Cytochrome P450 11B, mitochondrial (CP11B)453.32   NLR family CARD domain-containing protein 3 (NLRC3)−64.71
 Steroid 21-hydroxylase (CP21A)349.77   Keratin, type II cytoskeletal 8 (K2C8)−60.16
 Steroid 21-hydroxylase (CP21A)326.02   Translocase of chloroplast 34 homolog, chloroplastic (TOC34)−15.80
 Steroid 17-alpha-hydroxylase/17,20 lyase (CP17A)307.93   Carbonic anhydrase 1 (CAH1)−5.18
 Steroid 17-alpha-hydroxylase/17,20 lyase (CP17A)95.58  
 3 beta-hydroxysteroid dehydrogenase/Delta 5– > 4-isomerase type 1 (3BHSD)61.79  
 Nuclear receptor subfamily 5 group A member 2 (NR5A2)43.00  
Chemokine-like receptor 1 (CML1)17.97  
 Cholesterol side-chain cleavage enzyme, mitochondrial (CP11A)4.37  
72 hpi
 Acidic mammalian chitinase (CHIA)32.07   Contactin-associated protein-like 5 (CNTP5)−39.47
 Transposon Ty3-I Gag-Pol polyprotein (YI31B)10.35   Elongation factor 1-gamma (EF1G)−32.60
 Myosin-binding protein C, fast-type (MYPC2)6.51   Phosphoserine aminotransferase (PSAT)−6.24
 Fructose-bisphosphate aldolase A (ALDOA)5.12   Lanosterol 14-alpha demethylase (CP51A)−6.08
 Neuronal acetylcholine receptor subunit beta-4 (ACHB4)2.84   D-3-phosphoglycerate dehydrogenase (3-PGDH)−5.03
 Glyceraldehyde-3-phosphate dehydrogenase (G3P)2.75   Calreticulin (CALR)−4.42
 Rieske domain-containing protein (RFESD)2.08   Protein FAM111A (F111A)−4.16
     Calreticulin (CALR)−3.74
     Mitochondrial glutamate carrier 1 (GHC1)−3.43
     Arachidonate 12-lipoxygenase, 12R-type (LX12B)−3.20
     Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3)−3.06
     Fibronectin (FINC)−3.05
     Argininosuccinate synthase (ASSY)−3.04
     Quinone oxidoreductase PIG3 (QORX)−2.88
     Calreticulin (CALR)−2.76
     Stromal cell-derived factor 2-like protein 1 (SDF2L)−2.75
     Endoplasmic reticulum chaperone BiP (BIP)−2.71
     Inositol-3-phosphate synthase 1-A (INO1A)−2.69
     Protein disulfide-isomerase A6 (PDIA6)−2.63
     Spermidine synthase (SPEE)−2.62
     Nuclear mitotic apparatus protein 1 (NUMA1)−2.49
     Protein disulfide-isomerase A4 (PDIA4)−2.47
     Rac GTPase-activating protein 1 (RGAP1)−2.45
     L-lactate dehydrogenase A chain (LDHA)−2.40
     Histone chaperone asf1b-B (AS1BB)−2.36