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Table 4 Genes encoding neurotransmitter receptors significantly modulated in the brain after NNV infection.

From: RNA-Seq analysis of European sea bass (Dicentrarchus labrax L.) infected with nodavirus reveals powerful modulation of the stress response

Type of neurotransmitter receptorReceptor or related protein24 hpi72 hpi
Serotonin receptors5-hydroxytryptamine receptor 3E (5HT3E)51.82 
5-hydroxytryptamine receptor 5A (5HT5A) −3.19
5-hydroxytryptamine receptor 1F (5HT1F) −2.74
Glutamate receptorsN-methyl-d-aspartate (NMDA) NMDA 1 −2.35
N-methyl-d-aspartate (NMDA) NMDA 2A −2.77
N-methyl-d-aspartate (NMDA) NMDA 2B2.65−3.36
N-methyl-d-aspartate (NMDA) NMDA 2C 2.22
N-methyl-d-aspartate (NMDA) NMDA 2D −2.38
α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) AMPA1 (GluR-1) −2.32
α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) AMPA2 (GluR-2)2.05 
α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) AMPA3 (GluR-3) −2.68
α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) AMPA4 (GluR-4) −2,06
2-carboxy-3-carboxymethyl-4-isopropenylpyrrolidine (kainate) 5 (GluK5) −2,04
Metabotropic glutamate receptor 1 (mGluR1)2.12 
Metabotropic glutamate receptor 4 (mGluR4) −2,14
Metabotropic glutamate receptor 5 (mGluR5) −3.28
Metabotropic glutamate receptor 8 (mGluR8) −5.54
Vesicular glutamate transporter 1 (VGluT1)2.03 
Vesicular glutamate transporter 2.1 (VGL2A) −2.24
AMPA receptor-interacting protein GRIP1 2.10
Glutamate receptor-interacting protein 2 (GRIP2)2.012.01 &−2.05
Kainate-binding protein. Glutamate receptor U1 (GLRK)2.06 
Sodium-dependent glutamate/aspartate transporter 1 (EAA1, GLAST-1)2.51−2.39
GABA receptorsGABA(A) receptor subunit alpha-2 (GBRA2) −2.85
GABA(A) receptor subunit alpha-5 (GBRA5) −2.63
GABA(A) receptor subunit beta-1 (GBRB1) 4.26
GABA(A) receptor subunit beta-3 (GBRB3) −3.07
GABA(A) receptor subunit beta-4 (GBRB4) −2.41
GABA(A) receptor subunit pi (GBRP) −2.43
Acetylcholine receptorsMuscarinic acetylcholine receptor M2 (ACM2) −2.14
Neuronal acetylcholine receptor subunit alpha-3 (ACHA3) −3.14
Neuronal acetylcholine receptor subunit alpha-3 (ACHA3) −2.70
Neuronal acetylcholine receptor subunit alpha-7 (ACHA7) −3.24
Adrenergic receptorsAlpha-1B adrenergic receptor (ADA1B) −5.46
Alpha-2B adrenergic receptor (ADA2B) −2.01
Alpha-2Db adrenergic receptor (AA2DB) −2.70