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Figure 5 | Veterinary Research

Figure 5

From: Intranasally administered protein coated chitosan nanoparticles encapsulating influenza H9N2 HA2 and M2e mRNA molecules elicit protective immunity against avian influenza viruses in chickens

Figure 5

In vitro and in vivo safety evaluation of CNPs. A Hemolysis assay in chicken RBCs: 1. PBS control; 2–6, increasing concentrations of CNPs; 7, Triton-X 100 control. B Microscopy images of chicken RBCs incubated with PBS, different concentrations of CNPs, or Triton-X 100. C Effect of CNPs on chicken lungs. Chickens (n = 3 in each group) were intranasally administered with either PBS or CNPs, and after 5 days, their lungs were analyzed for histological changes. The experiment was repeated thrice. The results shown represent one independent experiment.

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Veterinary Research

ISSN: 1297-9716