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Table 2 Number of CD1b+, S100+, MHC-II+ and CD83+ cells in HLNs (medullary, paracortical and follicular areas) and livers expressed as the mean ± SD per area of 0.08 mm2per animal

From: Characterization of dendritic cells and follicular dendritic cells in the hepatic lymph nodes and liver of sheep experimentally infected with Fasciola hepatica

Antibody

Group

Medullary area HLNs

Paracortical area HLNs

Follicular area HLNs

Livers

CNA.42

UC

–

–

43.1 ± 11

–

9 dpi

–

–

71.6 ± 6.3

6.5 ± 10.8

18 dpi

–

–

93.2c ± 10.1

6.8 ± 10.1

CD1b

UC

6.2 ± 0.8

–

–

9 dpi

12.7 ± 2.2

–

2.1 ± 3.4

18 dpi

19.6c ± 4.6

–

5.7b ± 3.6

S100

UC

8.7 ± 2.6

9.0 ± 6.9

14.9 ± 10.1

1 ± 0.1

9 dpi

4.7 ± 0.9

5.8 ± 2.0

6.8 ± 4.3

2.3 ± 1.5

18 dpi

12.6b ± 1.5

16.3a ± 4.6

21.8a ± 7.1

3.9b ± 2.5

MHC-II

UC

19.8 ± 1.7

34.2 ± 1.5

16.1 ± 1.7

11.8 ± 9

9 dpi

13.4a ± 3.1

16.2a ± 3.8

1.6d ± 0.8

23.6b ± 5.5

18 dpi

1.9d ± 0.6

7.7d ± 4.2

0.2b ± 0.7

34d ± 9

CD83

UC

26.8 ± 6.4

53.1 ± 13.6

84 ± 10.4

0.6 ± 0.6

9 dpi

67.4b ± 10.7

27a ± 5.4

29.7a ± 9.4

2 ± 2.9

18 dpi

75b ± 9.8

34.5 ± 1.4

18.9a ± 2

4.9c ± 2.5

  1. CNA.42 is expressed as the number of positive cells per germinal centre. Statistical differences are in comparison with the UC group.
  2. UC: uninfected control group, dpi: days post-infection.
  3. a(P < 0.05), b(P < 0.01), c(P < 0.001), d(P < 0.0001).