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Figure 3 | Veterinary Research

Figure 3

From: Akkermansia muciniphila protects intestinal mucosa from damage caused by S. pullorum by initiating proliferation of intestinal epithelium

Figure 3

A. muciniphilaactivates gut growth and increases the proliferation of intestinal ISC after damage. A The colon lengths of chicks from the four treated groups. Treatment with A. muciniphila after S. pullorum significantly increased the colon length compared to S. pullorum. B Segments of the colon were processed to measure the crypt depth. Administration of S. pullorum decreased the crypt depth compared to the control group and treated with A. muciniphila significantly increased crypt depth. C Confocal images (PCNA staining, red; and DAPI staining, blue) of colon in intestine, more than 20 crypts were recorded, and the fluorescence intensity of PCNA was detected. Scale bars 200 μm.

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