Figure 2From: Effect of polymorphisms in porcine guanylate-binding proteins on host resistance to PRRSV infection in experimentally challenged pigsCorrelation between AUC (area under the curve) viremia and ADWG, AUC viremia and PRRSV viral loads in the serum and lungs, and ADWG. A The correlation (Spearman’s, r) between AUC viremia (0–21 dpc) and ADWG (until 28 dpc) was tested in the pigs after infection with JA142. B The viral loads in the serum samples collected from all pigs were quantified (using qRT-PCR) at 0 (before challenge), 3, 7, 14, 21 and 28 dpc. The viral loads are expressed as TCID50 equivalent/mL (log10). C ADWG in all pigs was calculated at every week up to 28 dpc and expressed as kg/day. D The lungs pathology (gross and microscopic lesions), and residual virus titers in the lung tissues collected from pigs at 28 dpc were measured using a microtitration infectivity assay performed in MARC-145 cells and presented as TCID50/mL (log10). The error bars represent the standard error of the mean (SEM). Asterisks indicate significant differences in each parameter among the genotypes (*p < 0.05). The bars showing different letters represent the values that differ significantly from each other (p < 0.05).Back to article page