Table 1 Distribution of clinical signs observed within the last month before euthanasia
From: Goats naturally devoid of PrPC are resistant to scrapie
Clinical sign | Scrapie-positive goats (PRNP+/+ and PRNP+/Ter) | Scrapie-negative goats (PRNPTer/Ter) | Barnard’s test p value |
|---|---|---|---|
Alopecia | 8/8 | 1/4 | 0.0005 |
Scratch test, positive | 7/8 | 0/4 | 0.006 |
Teeth grinding | 6/8 | 0/4 | 0.019 |
Head tests, overreactivity | 6/8 | 0/4 | 0.019 |
Menace response, decreased | 5/8 | 0/4 | NS (0.056) |
Aggression | 4/8 | 0/4 | NS (0.100) |
Swallowing reflex, reduced | 4/8 | 0/4 | NS (0.100) |
Depression | 2/8 | 0/4 | NS (0.425) |
Ataxia | 1/8 | 0/4 | NS (0.887) |