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Figure 3 | Veterinary Research

Figure 3

From: Nature and consequences of interactions between Salmonella enterica serovar Dublin and host cells in cattle

Figure 3

Effect of Salmonella infection on cell surface molecule expression. Single cell suspensions prepared from the ileum and LNs of the three calves challenged orally with SD3246-GFP were analysed for expression of several cell surface molecules. SD3246/GFP-infected cells in the A ileum and B LNs of infected calves showed increased surface expression of MHCII compared to uninfected cells in the same tissue as well as greater expression of CD40, CD80, CD86, CD11b and CD11c. At a tissue level only expression of MHCII and CD40 differed significantly between cells recovered from the C ileum and D LNs of infected and uninfected control calves. Low levels of CD80, CD86, CD11b and CD11c were detected in the tissues of both infected and uninfected calves and were not significantly different. *P < 0.05, ****< 0.001 and ****P < 0.0001.

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