Figure 3
Dot plots of data obtained from Triplex-WB of PrPres as in Figure 2. Each dot represents an individual goat TSE sample analysed in triplicate. Symbols: circles represent field cases and colour the country of origin; other symbols represent experimental samples and control samples from sheep or goat. A Plot with marker for N terminus epitope level on vertical axis versus PrPres double triplets marker on horizontal axis. Horizontal and vertical broken lines indicate the clear separation between CS, CH1641 and BSE. The lower N-terminus marker values of Italian cases and F16 are striking (encircled). B Triplet glycoprofile markers with non-glycosylated (N) fraction on vertical axis and on horizontal axis the ratio between signals in mono-glycosylated (M) and di-glycosylated fraction (D). A difference is obvious between BSE cases (low N and low M/D, due to high D levels in BSE samples) with CS and CH1641 cases.