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Table 1 Protection induced by Rev1::Tn7wbdRΔwbkC against B. ovis

From: Rev1 wbdR tagged vaccines against Brucella ovis

Vaccine (dose)

Mean ± SD of log10 CFU in spleen of:

Units of protection

B. ovis

Vaccine

Rev1 (105)

2.45 ± 1.35a

2.82 ± 0.99

3.81

Rev1::Tn7wbdRΔwbkC (105)

4.47 ± 1.40

0.69 ± 0.09c

1.79

Rev1::Tn7wbdRΔwbkC (108)

2.16 ± 0.95a, b

0.90 ± 0.53c

4.10

PBS (unvaccinated)

6.26 ± 0.16

 

0.00

  1. Statistical comparison (n = 5) of mean log10 B. ovis CFU/spleen: ap < 0.001 vs. PBS (unvaccinated), bp > 0.05 vs. Rev1 and log10 vaccine CFU/spleen c p < 0.01 vs. Rev1.