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Table 1 Effect of 3-BrPA on biochemical parameters of BALB/c mice after 6 weeks of oral administration

From: In vitro and in vivo effects of 3-bromopyruvate against Echinococcus metacestodes

Parameters

Untreated

ABZ treated

3-BrPA treated

TBIL (μM/L)

2.257 ± 0.232

2.071 ± 0.437

2.25 ± 0.206

DBIL (μM/L)

1.157 ± 0.396

1.000 ± 0.346

1.267 ± 0.359

IBIL (μM/L)

1.100 ± 0.227

1.071 ± 0.281

0.983 ± 0.380

TP (g/L)

57.786 ± 1.89

54.900 ± 2.196*

58.65 ± 1.447

ALB (g/L)

32.257 ± 1.011

30.942 ± 0.972*

32.667 ± 0.624

GLB (g/L)

25.529 ± 2.175

23.957 ± 1.987

25.983 ± 1.061

ALP (U/L)

92.571 ± 9.256

118.000 ± 45.997

95.167 ± 14.554

ALT (U/L)

26.833 ± 7.151

41.429 ± 19.617

35.717 ± 10.517

AST (U/L)

115.500 ± 18.355

148.000 ± 27.475*

129.167 ± 8.783

GGT (U/L)

1.543 ± 0.475

1.614 ± 0.706

1.267 ± 0.269

UREA (mM/L)

9.711 ± 1.249

9.154 ± 1.847

10.330 ± 1.492

CREA (μM/L)

27.886 ± 4.362

29.714 ± 3.862

28.050 ± 2.862

  1. Data given as Mean ± SD of seven animals.
  2. * Value significantly differs at 95% levels of significance (p < 0.05) for ABZ vs. untreated control.