Table 3 Genes that were characteristic of the S. ruminantium isolates from diseased tissue sites
COG IDa | Annotation | Conserved domain and/or description on blast hits | Isolation sites | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Heart | Liver abscess | Pulmonary abscess | Joint | Lung | |||||||||
DAT741 | DTK364 | DTK390 | DTK285 | DTK284 | EA1832.92 | MO591 | DTK360 | DTK397 | DTK366 | DAT837 | |||
fhaB | Iron-regulated surface protein | pfam04650: YSIRK_signal; YSIRK type signal peptide cl27124: IsdB super family; haem uptake protein IsdB | + | + | + | + | + | + | + | + | – | – | + |
group_1846 | Peptide-binding protein | cd08510: PBP2_Lactococcal_OppA_like; the substrate binding component of an ABC-type lactococcal OppA-like transport system | + | + | + | + | + | + | + | – | – | + | + |
group_669 | Hypothetical protein | Imm70 super family cl21402 Immunity protein 70 | + | + | + | + | + | + | – | – | – | – | + |
group_1859 | DNA-binding response regulator | CitB COG2197 DNA-binding response regulator Similar to SalR of S. suis SC84 (Amino acid similarity, 86%; coverage, 100%) | + | + | + | + | + | + | – | – | – | – | + |
group_1860 | Histidine kinase | HisKA_3 super family cl26854 Histidine kinase Similar to SalK of S. suis SC84 (Amino acid similarity, 84%; coverage, 100%) | + | + | + | + | + | + | – | – | – | – | + |
group_1861 | ABC transporter permease | No conserved domain Blast hit with ABC transporter permeases of several species | + | + | + | + | + | + | – | – | – | – | + |
group_1862 | ABC transporter permease | No conserved domain Blast hit with ABC transporter permeases of several species | + | + | + | + | + | + | – | – | – | – | + |
group_1863 | ABC transporter | ABC_ATPase super family cl25403 ATP-binding cassette transporter nucleotide-binding domain | + | + | + | + | + | + | – | – | – | – | + |
group_1864 | ABC transporter | SunT super family cl26602 ABC-type bacteriocin/lantibiotic exporters | + | + | + | + | + | + | – | – | – | – | + |
group_391 | Lantibiotic-modifying protein | LanC_like super family cl04955 Cyclases involved in the biosynthesis of lantibiotics | + | + | + | + | + | + | – | – | – | – | + |
group_1865 | Columbicin A-like bacteriocin peptide | L_biotic_typeA super family cl04622 Type-A lantibiotic | + | + | + | + | + | + | – | – | – | – | + |
COG IDa | Annotation | Conserved domain and/or description on blast hits | Tonsils or oral cavity | Heart | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MO402 | DTK377 | MO430 | MO449 | MO492 | MO498 | MO505 | MO512 | MO533 | MO557 | GUT187b | |||
fhaB | Iron-regulated surface protein | pfam04650: YSIRK_signal; YSIRK type signal peptide cl27124: IsdB super family; haem uptake protein IsdB | – | + | – | – | – | – | + | – | – | + | + |
group_1846 | Peptide-binding protein | cd08510: PBP2_Lactococcal_OppA_like; the substrate binding component of an ABC-type lactococcal OppA-like transport system | – | – | – | – | – | – | + | – | – | + | + |
group_669 | Hypothetical protein | Imm70 super family cl21402 Immunity protein 70 | – | + | – | – | – | – | + | + | – | – | + |
group_1859 | DNA-binding response regulator | CitB COG2197 DNA-binding response regulator Similar to SalR of S. suis SC84 (Amino acid similarity, 86%; coverage, 100%) | – | + | – | – | – | – | + | + | – | – | + |
group_1860 | Histidine kinase | HisKA_3 super family cl26854 Histidine kinase Similar to SalK of S. suis SC84 (Amino acid similarity, 84%; coverage, 100%) | – | + | – | – | – | – | + | + | – | – | + |
group_1861 | ABC transporter permease | No conserved domain Blast hit with ABC transporter permeases of several species | – | + | – | – | – | – | + | + | – | – | + |
group_1862 | ABC transporter permease | No conserved domain Blast hit with ABC transporter permeases of several species | – | + | – | – | – | – | + | + | – | – | + |
group_1863 | ABC transporter | ABC_ATPase super family cl25403 ATP-binding cassette transporter nucleotide-binding domain | – | + | – | – | – | – | + | + | – | – | + |
group_1864 | ABC transporter | SunT super family cl26602 ABC-type bacteriocin/lantibiotic exporters | – | + | – | – | – | – | + | + | – | – | + |
group_391 | Lantibiotic-modifying protein | LanC_like super family cl04955 Cyclases involved in the biosynthesis of lantibiotics | – | + | – | – | – | – | + | + | – | – | + |
group_1865 | Columbicin A-like bacteriocin peptide | L_biotic_typeA super family cl04622 Type-A lantibiotic | – | + | – | – | – | – | + | + | – | – | + |