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Figure 4 | Veterinary Research

Figure 4

From: Host-range shift of H3N8 canine influenza virus: a phylodynamic analysis of its origin and adaptation from equine to canine host

Figure 4

ML tree of the H3N8 CIV concatenated full genome. From the dataset of the 44 full viral genome sequences, after splicing for segments M and NS, the segments were concatenated (HA, M1, NA, NP, NS1, PA, PB1, and PB2) for each virus, followed by the generation of a maximum-likelihood (ML) tree. The tree was constructed using the HKY + gamma nucleotide substitution model with 1000 bootstrap replications. Insert: Regression analysis of branch-length to year of virus isolation. Colour rectangles indicate different clades: clade I (yellow), clade II (pink), clade III (brown), clade IV (blue), clade V (green), clade VI (purple).

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