Table 2 Gross and histopathological analysis of TBL in lung and pulmonary lymphoid nodes

Lung

 Median no. of lobes affected

3.5 (IQR 1–4)

1 (IQR 0.8–1)*

2 (IQR 1–2.5)

 Median score

4 (IQR 1–5.8)

1 (IQR 0.8–1.3)*

2 (IQR 1–4)

 No. animals with TBL

10/11 (83.3%)^b

3/14 (21.4%)*

8/13 (61.5%)

 Development stage of granulomas

  I

0/11 (0%)

0/14 (0%)

0/13 (0%)

  II

1/11 (9.1%)

0/14 (0%)

3/13 (23.1%)

  III

2/11 (18.2%)

0/14 (0%)

0/13 (0%)

  IV

7/11 (63.6%)

3/14 (21.4%)*

5/13 (38.5%)

 Mean of MNGCs^a

7 (± 8.1)

1.6 (± 3.7)*

5.1 (± 8)

 No. animals with satellite granulomas

0/11 (0%)

1/14 (7.1%)

0/13 (0%)

Pulmonary LNs

 Median score

6.5 (IQR 4.3–9.8)

2 (IQR 1–3.3)*

2 (IQR 2–4)*

 No. animals with TBL

11/11 (100%)^b

8/14 (57.1%)*

10/13 (76.9%)

 Development stage of granulomas

  I

0/11 (0%)

0/14 (0%)

1/13 (7.7%)

  II

1/11 (9.1%)

0/14 (0%)

0/13 (0%)

  III

1/11 (9.1%)

0/14 (0%)

0/13 (0%)

  IV

9/11 (81.8%)

8/14 (57.1%)

9/13 (69.2%)

 Mean of MNGCs

10.7 (± 6.9)

3.71 (± 5.52)*

9.1 (± 11.7)

 No. animals with satellite granulomas

5/11 (45.5%)

1/14 (7.1%)

4/13 (30.8%)