Figure 9

A model illustrating BEFV-induced autophagy signaling pathways. BEFV triggers autophagy to benefit viral production through either activation of the PI3K/Akt/NF-κB or Src/JNK/AP-1 pathways in the early to middle stages of infection (A, B) as well as suppression of the PI3K/Akt/mTOR complex 1 in the late stage of infection (C).