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Figure 6 | Veterinary Research

Figure 6

From: Bovine ephemeral fever virus triggers autophagy enhancing virus replication via upregulation of the Src/JNK/AP1 and PI3K/Akt/NF-κB pathways and suppression of the PI3K/Akt/mTOR pathway

Figure 6

BEFV induces autophagy through upregulation of the Src/JNK/AP-1 pathway. A MDBK cells were infected with BEFV at a MOI of 1 and cell lysates were collected individually at the indicated time points for immunoblotting with the respective antibodies. B MDBK cells were pretreated with AP-1 inhibitor Tanshinone and the cell lysates were collected individually at 4 hpi for immunoblotting with the respective antibodies. The levels of the indicated proteins in the mock controls (0 h or un-treatment) were considered onefold. The protein levels were normalised to those for β-actin. The activation and inactivation folds indicated below each lane were normalized against values for the mock control.

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Veterinary Research

ISSN: 1297-9716