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Table 1 Clinical outcome, serology, histopathology, and parasite detection in tissues for Nc-Spain7 infected foetuses and calves

From: Effects of challenge dose and inoculation route of the virulent Neospora caninum Nc-Spain7 isolate in pregnant cattle at mid-gestation

Group (dose, route) Animal ID Foetal death (dpi)/calf N. caninum-specific IgG Histopathology (HE, IHQ) N. caninum DNA detection
IFAT titreb RIPC Placentome Brain Liver
IV1 (107 tachyzoites) IV1.1 Foetal death (31) + 9/9 3/3 0/3
IV1.2 Foetal death (25) + 9/9 3/3 0/3
IV1.3 Foetal death (27) ND ND ND ND ND
IV1.4 Calf 3200 14.4 0/10 0/3
IV1.5 Calf 800 7.8 2/10 0/3
IV1.6 Foetal death (30) + 9/9 3/3 0/3
IV2 (105 tachyzoites) IV2.1 Foetal death (29) ND + 8/8 3/3 1/3
IV2.2 Foetal death (39) + 9/9 3/3 0/3
IV2.3 Calf 3200 48.5 0/10 0/3
IV2.4 Calf − 2.5 0/10 0/3
IV2.5 Foetal death (39) 16 + 7/9 3/3 0/3
IV2.6 Calf 6400 60.5 0/10 0/3
SC (105 tachyzoites) SC.1 Calf − 4.4 0/10 0/3
SC.2 Foetal death (26) 9/9 3/3 1/3
SC.3 Calf − 4.4 0/10 0/3
SC.4 Calf − 4.1 0/10 0/3
SC.5 Calf − 3.5 0/10 0/3
SC.6 Calf − 4.5 0/10 0/3
IV3 (103 tachyzoites) IV3.1 Calf − 2.9 0/10 0/3
IV3.2 Calf − 3.1 0/10 0/3
IV3.3 Foetal death (38) ND + 8/9 0/3 ND
IV3.4 Calf − 3.2 0/10 0/3
IV3.5 Calf 50 − 3.3 0/10 0/3
IV3.6 Calf − 3.1 0/10 0/3
IV4 (102 tachyzoites) IV4.1 Foetal death (62) 32 + 8/9 0/3 0/3
IV4.2 Foetal death (42) + 8/9 3/3 0/3
IV4.3 Calf − 2.9 0/10 0/3
IV4.4 Calf − 3.2 4/10 0/3
IV4.5 Calf − 3.7 4/10 0/3
  1. ID: identification, ND: no data are available, IV: intravenous, SC: subcutaneous, HE: haematoxylin–eosin, IHQ: immunohistochemical labelling.