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Figure 5 | Veterinary Research

Figure 5

From: The immunomodulatory functions and molecular mechanism of a new bursal heptapeptide (BP7) in immune responses and immature B cells

Figure 5

BP7 induced autophagy and enhanced AMPK-ULK1 phosphorylation and BCL-2 expression in WEHI-231 cells. A Transmission electron microscopy of autophagosome formation in WEHI-231 cells treated with 10 μg/mL BP7. The arrow indicates autophagosomes in WEHI-231 cells. B LC3 protein expression. C AMPK-ULK1 phosphorylation. D Expression levels of BCL-2. In B and C, WEHI-231 cells treated with 10 μg/mL BSA were used as the irrelevant control (Control), and those treated with rapamycin were used as the positive control. In D, WEHI-231 cells treated with 10 μg/mL BSA were used as the irrelevant control (Control), and those treated with Dox were used as the positive control. Representative Western blots are shown.

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Veterinary Research

ISSN: 1297-9716